Achievment

Publications  (*, Corresponding author)

• Tokumaru T, Apolinario MEC, Shimizu N, Umeda R, Honda K, Shikano K, Teranishi H, Hikida T, Hanada T, Ohta K, Li Y, Murakami K, Hanada R*.
  Hepatic extracellular　ATP/adenosine dynamics in zebrafish models of alcoholic and metabolic steatotic liver
  Sci Rep. 14:7813. 2024
• Okanari K, Teranishi H, Umeda R, Shikano K, Inoue M, Hanada T, Ihara K, Hanada R*.
  Behavioral and neurotransmitter changes on antiepileptic drugs treatment in the zebrafish pentylenetetrazol-induced seizure model.
  Behav Brain Res.  464:114920, 2024
• Ikeuchi M, Inoue M, Miyahara H, Sebastian WA, Miyazaki S, Takeno T, Kiyota K,Yano S, Shiraishi H, Shimizu N, Hanada R, Yoshimura A, Ihara K, Hanada T.
  A pH　imbalance is linked to autophagic dysregulation of inner ear hair cells in　Atp6v1ba-deficient zebrafish.
  Biochem Biophys Res Commun. 699:149551, 2024
• Carrasco Apolinario ME, Umeda R, Teranishi H, Shan M, Phurpa, Sebastian W.A, Lai S, Shimizu N, Shiraishi H, Shikano K, Hikida T, Hanada T, Ohta K, Hanada R*.
  Behavioral and neurological effects of Vrk1 deficiency in zebrafish.
  Biochem Biophys Res Commun. 675: 10-18, 2023
• Ikeda N, Kawasaki M, Baba K, Nishimura H, Fujitani T, Suzuki H, Matsuura T, Ohnishi H, Shimizu M, Sanada K, Nishimura K, Yoshimura M, Maruyama T, Conway-Campbell BL, Onaka T, Teranishi H, Hanada R, Ueta Y, Sakai A.
  Chemogenetic Activation of Oxytocin Neurons Improves Pain in a Reserpine-induced Fibromyalgia Rat Model.
  Neuroscience. 528:37, 2023
• Umeda R, Teranishi H, Hada K, Shimizu N, Shiraishi H, Urushibata H,Lai S, Shide M, Carrasco Apolinario ME, Higa R, Shikano K, Shin T,Mimata H, Hikida T, Hanada T, *Hanada R.
  Vrk2 deficiency elicits aggressive behavior in female zebrafish.
  Genes Cells. 27(4): 254-265, 2022
• Teranishi H, Hanada R.
  Neuromedin U, a Key Molecule in Metabolic Disorders.
  Int J Mol Sci. 22(8): 4238, 2021
• Anan M, Higa R, Shikano K, Shide M, Soda A, Carrasco Apolinario ME, Mori K,Shin T, Miyazato M, Mimata H, Hikida T, Hanada T, Nakao K, Kangawa K,*Hanada R.
  Cocaine has some effect on neuromedin U expressing neurons related to the brain reward system. Heliyon 6(5): e03947, 2020
• Fujinami H, Shiraishi H, Hada K, Inoue M, Morisaki I, Higa R, Shin T, Kobayashi T, Hanada R, Penninger JM, Mimata H, *Hanada T.
  CLP1 acts as the main RNA kinase in mice.
  Biochem Biophys Res Commun.525(1): 129-134, 2020
• Inoue M, Hada K, Shiraishi H, Yatsuka H, Fujinami H, Morisaki I, Matsibara E,Ishitani T, Hanada R, Matsumoto M, Penninger JM, Ihara K, *Hanada T.
  Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2.
  Biochem Biophys Res Commun. 525(3)：726-732, 2020
• Yatsuka H, Hada K, Shiraishi H, Umeda R, Morisaki I, Urushibata H, Shimizu N,Sebastian W.A, Hikida T, Ishitani T, Hanada R, Shimada T, Kimoto K, Kubota T,*Hanada T.
  Exosc2 deficiency leads to developmental disorders by causing a nucleotide pool
  imbalance in zebrafish.
  Biochem Biophys Res Commun. 533(4): 1470-1476, 2020
• *Hanada R.
  The role of the RANKL/RANK/OPG system in the central nervous systems (CNS).
  J Bone Miner Metab. 39(1): 64-70, 2021
• Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A,Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N,Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ,She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K,*Kroemer G, *Penninger JM.
  AIF-regulated oxidative phosphorylation supports lung cancer development.
  Cell Res. 29(7): 579-591, 2019
• Higa R, *Hanada T, Teranishi H, Miki D, Seo K, Hada K, Shiraishi H, Mimata H, Hanada R, Kangawa K, Murai T, Nakao K. CD105
  maintains the thermogenic program of beige adipocytes by regulating
  Smad2 signaling.
  Molecular Cellular Endocrinology. 15; 474:184-193,2018
• Teranishi H, Hayashi M, Higa R, Mori K, Miyazawa T, Hino J, Amano Y, Tozawa R, Ida T, Hanada T, Miyazato M, *Hanada R, Kangawa K, Nakao K.
  Role of neuromedin U in accelerating of non-alcoholic steatohepatitis in mice. Peptides. 99: 134-141, 2018

Invited talks

• Hanada R
  The 22nd Meeting of the Japan Endocrine Society of the Kyushu Branch,
  September 3rd, 2022, Kumamoto
• Hanada R
  The 43rd Annual Meeting of the Japan Society for the Study of Obesity / The
  40th Annual Meeting of the Japanese Society for the Treatment of Obesity, December 2nd, 2022, Okinawa
• Hanada R
  The Faculty Development Seminar of the Kyushu University Graduate
  school of Medical sciences, December 21st , 2022, WEBINAR(LIVE)
• Umeda R
  The 6th Japan-Thailand Academic Exchange Seminar, December 12th ,
  2022, Oita

Awards

• APPW2025（Anatomy-Physiology-Pharmacology Week in 2025）,Undergraduate Poster Award
  Awardee: Ami Kato
  Title of study: Ketone bodies improve alcoholic liver disease by reducing extracellular hepatocyte ATP/adenosine levels in Zebrafish
• The 31st Annual Meeting of the Western Japan Society for the study on Obesity, Young Investigator Awards (YIA）
  Awardee: Kenshiro Shikano
  Title of study: Role of hypothalamic NPGL/NPGM system on the regulation of feeding and energy metabolism
• The 49th Annual Meeting of the Japan Neuroendocrine Society, Young Investigator Awards (YIA）
  Awardee: Kenshiro Shikano
  Title of study:Physiological mechanisms of energy metabolism in NPGL/NPGM double knockout mice that exhibit leanness

Fundings

• Grant-in-Aid for JSPS fellows (KAKENHI)
  Funding agency: The Ministry of Education, Culture, Sports, Science and Technology (MEXT)
  PI: Reiko Hanada
  FY: 2024~2025
• Grant-in-Aid for Transformative Research Areas (B) (KAKENHI)
  Funding agency: The Ministry of Education, Culture, Sports, Science and Technology (MEXT)
  PI: Reiko Hanada
  FY: 2021~2024
• Grant-in-Aid for Transformative Research Areas (C) (KAKENHI)
  Funding agency: The Ministry of Education, Culture, Sports, Science and Technology (MEXT)
  PI: Kenshiro Shikano
  FY: 2023~2025
• Grant-in-Aid for Transformative Research Areas (C) (KAKENHI)
  Funding agency: The Ministry of Education, Culture, Sports, Science and Technology (MEXT)
  PI: Hitoshi Teranishi
  FY: 2023~2025

Press Releases and Media Coverage

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• @title @@@@. NHK, Date: mmmm, dddd, 202@,
• @title@@@. Released by Oita University, date: mmmm, dddd, 202@